A team of researchers concluded that tarantula venom could be used as an alternative to opioid-based painkillers among patients seeking chronic pain relief.
According to the study, which was published in the Journal of Biological Chemistry, researchers from the University of “Queensland” Australian designed a new small protein for the poison of “tarantulas” that can relieve severe pain without addiction.
The researchers said that the current opioid crisis around the world means the urgent need for urgent alternatives to morphine drugs, such as “fentanyl” and “oxycodone”.
“Although opiates are effective in producing painkillers, they come with unwanted side effects, such as nausea, constipation and the risk of addiction, which puts a heavy burden on society,” said researcher Christina Schroeder from the University of Queensland.
“Our study found that a small protein in the venom of tarantulas binds to pain receptors in the body, and by using a three-dimensional approach in designing our drugs that includes the mini protein, its receptor and the surrounding membrane of spider venom, we altered this mini protein to increase the effectiveness and specificity of specific pain receptors,” she added. This ensures that only the right amount of microparticle is attached to the receptor and the cell membrane surrounding the pain receptors.
The researchers pointed out that “the mini-protein was tested in mouse models and proved that it works effectively,” saying, “Our results can lead to an alternative method of treating pain without side effects and reduce the dependence of many individuals on opioids for pain relief.”
Australian scientists have discovered that dangerous spider venom may help treat stroke patients.
Scientists specializing in biochemistry found that this toxin gave better chances for survival.
Scientists say that the venom of the web spider, a killer spider found on the Australian island of Friars, contains a molecule that helps stop the effect of a stroke on the brain.
According to university professor Glenn King, from the University of Queensland, the new drug can be used by paramedics easily within minutes to protect the brain.